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HIV and Its Treatment

Testing HIV Positive – Do I Have AIDS?
Seeing an HIV Doctor
Starting Anti-HIV Medications
Recommended HIV Treatment Regimens
Approved Medications to Treat HIV Infection
Is My Treatment Regimen Working?
HIV Treatment Regimen Failure
Changing My HIV Treatment Regimen
What is Treatment Adherence?
Adhering To My HIV Treatment Regimen
HIV and Pregnancy
Understanding HIV Prevention

What is Treatment Adherence?

What is adherence?

Adherence refers to how closely you follow a prescribed treatment regimen. It includes your willingness to start treatment and your ability to take medications exactly as directed.

Is adherence important for HIV treatment?

Yes! Adherence is a major issue in HIV treatment for two reasons:

Adherence affects how well anti-HIV medications decrease your viral load. When you skip a medication dose, even just once, the virus has the opportunity to reproduce more rapidly. Keeping HIV replication at a minimum is essential for preventing AIDS-related conditions and death.

Adherence to HIV treatment helps prevent drug resistance. When you skip doses, you may develop strains of HIV that are resistant to the drugs you are taking and even to drugs you have not yet taken. This may leave you with fewer treatment options should you need to change treatment regimens in the future. Because drug-resistant strains can be transmitted to others, engaging in risky behavior can have especially serious consequences.

Although there are many different anti-HIV medications and treatment regimens, studies show that your first regimen has the best chance for long-term success. Taking your drugs correctly (adherence) increases your odds of success.

Why is adherence difficult for many people with HIV?

HIV treatment regimens can be complicated; most regimens involve taking multiple pills each day. Some anti-HIV medications must be taken on an empty stomach, while others must be taken with meals. This can be difficult for many people, especially for those who are sick or are experiencing HIV symptoms or negative drug side effects.

Other factors that can make it difficult to adhere to an HIV treatment regimen include:

Experiencing unpleasant medication side effects (such as nausea)
Sleeping through doses
Traveling away from home
Being too busy
Feeling sick or depressed
Forgetting to take medications

What can I do to adhere to my treatment regimen?

There are many things you can do to better adhere to your treatment regimen.

One of the most important things you can do when starting a treatment regimen is to talk with your doctor about your lifestyle. He or she will then be able to prescribe a regimen that works best for you. Topics you should address with your doctor include:

Your travel, sleep, and eating schedule
Possible side effects of medication
Other medications you are taking and their possible interaction with anti-HIV medications
Your level of commitment to following an HIV treatment regimen

Many people adhere well to their treatment early on, but find adherence becomes more difficult over time. Talk with your doctor about adherence during every visit. Your commitment to a treatment plan is critical; studies show that patients who take their medications correctly achieve the best results.

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