Bronchodilators
Summary
About bronchodilators
Types and differences
Conditions treated
Conditions of concern
Potential side effects
Drug and other interactions
Symptoms of overdose
Lifestyle considerations
Pregnancy use issues
Child use issues
Elderly use issues
The form and severity of side effects will vary depending on the type of
bronchodilator. High doses of short–acting beta2 agonists, for instance, have
been associated with hypokalemia (low potassium levels in the blood, which can
result in weakness) and abnormal heart rhythms.
Recently, a large clinical study found that the long–acting salmeterol drug
was associated with a small, but significant, increased risk of death in asthma
patients. The U.S. Food and Drug Administration is continuing to investigate the
drug, and warns patients NOT to stop taking prescribed medication without first
consulting their physician.
Patients taking bronchodilators are advised to call their physicians
immediately if they experience any of the following symptoms:
Chest pain
Severe headache
Severe vomiting
Fever or chills
Fast or pounding heartbeat
Skin rash
Hives
Hoarseness
Choking or difficulty swallowing
Loud or high–pitched breathing
Worsening of symptoms
Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or
lower legs.
Less serious side effects should be brought to the attention of a physician
and may include:
Headache
Anxiety, nervousness, agitation or hyperactivity
Muscle cramps or tremors
Coughing
Dizziness or light–headedness
Dryness or irritation of mouth or throat
Unpleasant taste
Nausea, stomach ache or vomiting
Pinkish–red saliva (isoproterenol only)
Elevated blood pressure
Diarrhea
Difficulty urinating
Tingling of the hands and feet
Arching of the back
In addition, certain bronchodilators may cause temporary blurred vision if
the medication comes into direct contact with the eyes.
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Patients should consult their physicians before taking any additional
prescriptions, over–the–counter medications, nutritional supplements or
herbal medications. Of particular concern to individuals taking bronchodilators
are:
Antihypertensives (medications to treat high blood pressure). Bronchodilator
use may lessen the effectiveness of these drugs.
Antiarrhythmics (medications to treat abnormal heart beats). Bronchodilators
used in conjunction with these drugs may lessen their effectiveness.
Antibiotics (medications to treat bacterial infection). These medications may
interfere with the function of bronchodilators.
Anti–seizure medications. Bronchodilator use may lessen the effectiveness
of these drugs.
Ulcer medications. These medications may interfere with the function of
bronchodilators.
Psychiatric medications. Use of some bronchodilators in conjunction with
certain medications used to treat psychiatric disorders may lead to a
potentially dangerous drop in blood pressure and/or rapid heartbeat.
Smoke. Smoking or exposure to second–hand smoke can interfere with the way
the body responds to certain bronchodilators.
Caffeine. Coffee, tea, colas and other caffeinated drinks can change the
effectiveness of certain bronchodilators.
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Symptoms of overdose can be similar to the medication’s side effects, but
are usually more severe. Patients exhibiting any of these symptoms should
contact their physicians immediately:
Convulsions
Problems breathing
Blue lips and fingernails
Continued blurred vision, dilated pupils
Low blood pressure
Chest pain
Severe headache
Vomiting and nausea
Rapid heartbeat
For less severe symptoms that do not indicate overdose but require contacting
a physician.
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