Bronchodilators
Summary
About bronchodilators
Types and differences
Conditions treated
Conditions of concern
Potential side effects
Drug and other interactions
Symptoms of overdose
Lifestyle considerations
Pregnancy use issues
Child use issues
Elderly use issues
Patients or caregivers of patients using bronchodilators need to know how to
monitor and measure responses to these medications. The correct use and
maintenance of devices such as nebulizers, peak flow meters and inhalers are
very important.
Teenagers sometimes perceive a stigma associated with inhaler therapy because
it can make them feel different, not well or not part of the group. Parents may
wish to point out that many asthmatic athletes use bronchodilators and such
people are proof that it is still possible to participate and excel in physical
activities. People any age taking bronchodilators are encouraged to discuss
their concerns and activity levels with their physicians.
Some adolescents may deny having asthma or other breathing disorders that
require bronchodilators and discontinue taking their medications. Caregivers
need to be aware of this issue and monitor medication use until the adolescent
is ready to manage his or her own care. Because bronchodilators are basically
rescue medications, users need to have their medications with them at all times.
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Certain bronchodilators are used to treat asthma in pregnant women, including
albuterol, bitolterol, formoterol, metaproterenol and salmeterol. Although there
have been no studies on birth defects in humans, and no reported cases
definitively linking birth defects to bronchodilators, some animal studies
involving bronchodilators report birth defects when given in doses many times
higher than human doses.
Pregnant women who were given epinephrine under the skin have had more birth
defects than expected in some studies, although the severity of the mother’s
asthma may have contributed to this result.
The medicines fenoterol, isoproterenol, pirbuterol, procaterol and
terbutaline have not been shown to cause birth defects in animal studies. Women
taking bronchodilators who are pregnant or wish to become pregnant are
encouraged to discuss potential benefits and risks with their physician.
It is not known at this time whether bronchodilators pass into the breast
milk. Although most medicines pass into breast milk in small amounts, many of
them are considered safe for nursing infants. Mothers who use bronchodilators
and who wish to breast–feed are encouraged to discuss this with their
physician.
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Generally, bronchodilators are used on an as–needed basis when there is
difficulty breathing or a child is having trouble with coughing or wheezing. If
a child wheezes or coughs only after exercising, he or she may have
exercise-induced asthma.
Studies performed to date have not demonstrated specific problems that would
limit the usefulness of bronchodilators in children. However, isoetharine is not
recommended for their use. Bronchodilators routinely prescribed for children
include: albuterol, bitolterol, levalbuterol, proventil, pirbuterol, terbutaline,
levalbuterol.
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The medicine salmeterol has been tested in a limited number of patients 65
years of age or older and has not been shown to cause different side effects or
problems in older people than it does in younger adults.
The medicines albuterol, bitolterol, epinephrine, fenoterol, isoetharine,
isoproterenol, metaproterenol, pirbuterol, procaterol, and terbutaline have not
been studied specifically in older adults. It is not known whether or not they
work exactly the same way as they do in younger adults or if they cause
different side effects among the older adult population.
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